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consequences_of_receptor_activation_fall_08

consequences_of_receptor_activation_fall_08 - phosphatases...

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Consequences of Receptor Activation A cascade of cytoplasmic signal amplification steps is initiated The cascade often involves phosphorylation (by protein kinases; ~ 500 genes in human genome) and dephosphorylation (by
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Unformatted text preview: phosphatases; ~ 100 genes) of regulatory proteins and enzymes. Nearly 50% of all cellular proteins, both cytoplasmic and transmembrane are phosphorylated at one or more sites (serine; threonine, tyrosine)....
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