b1_secondary_structure_

b1_secondary_structure_ - Question...

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Question: How is it possible that many different linear sequences of amino acids can form the same secondary structure (alpha helices, beta sheets, random coils, etc.)?
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Primary Structure!! The sequence of amino acids Contains all the information needed to fold the peptide chain into its native conformation The composition of amino acids and the order in which they occur determines which secondary structure is formed.
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Formation of Secondary Structures Mainly formed by hydrogen bond interactions between amino acid residues These bonds must stabilize the folding of the peptide backbone
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Alpha Helix The carbonyl of one residue bonds to the amine group four residues farther up the chain.
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Alpha Helix All of the hydrogen bonds lie parallel to the helical axis with all the carbonyl groups pointing in one direction along the axis and all the H—N groups pointing in the other.
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Certain amino acids or sequences can have certain properties that make them alpha helix formers or
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This note was uploaded on 10/20/2009 for the course BIS 102 taught by Professor Hilt during the Summer '08 term at UC Davis.

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b1_secondary_structure_ - Question...

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