This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: pharmacologically useful, a number of derivatives prepared by introducing R and R' groups into the diethyl malonate are used as drugs. Doses of these barbiturates of 100 mg often will induce sleep. A lethal dose for an average size human is about 1500 mg. In combination with ethyl alcohol, barbiturates are extremely dangerous producing a dramatic depressant effect on humans that can cause death. Barbiturates also are addictive. N O N O = C 2 H 5 C 6 H 5 N O N O CH 2 =CHCH 2 CH 3 CH 2 CH 2 CH CH 3 barbital induces sleep in dogs phenobarbital sedative for humans, used as anti-convulsant in treatment of epilepsy secobarbital (seconal) a sedative H H H H O O N O N O C 2 H 5 C 2 H 5 H H O...
View Full Document
This note was uploaded on 10/20/2009 for the course CHEM 322BL at USC.
- Organic chemistry