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Unformatted text preview: yields secondary and tertiary amides, respectively. RCCl O = + 2 R'NH 2 primary amine RCNHR' + R'NH 3 + Cl-O secondary amide an N-substituted amide RCCl O + 2 R'R''NH secondary amine RCNR'R'' + R'R''NH 2 + Cl-O tertiary amide an N,N-disubstituted amide Note: Two equivalents of the amine are required for complete reaction. Tertiary amines react with acyl chlorides to produce salts, not stable amide products. RCCl O + R' 3 N: RCNR' 3 Cl-O + an acylammonium chloride...
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- Organic chemistry, Amine, Amide, acyl chlorides, tertiary amides