This preview shows pages 1–3. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: salicyclic acid with acetic anhydride: : O : = H C-Na + O . . . . . . O . . . . OH Na + C-O . . . . . . O . . . . sodium salicylate : O :-Na + C O O The phenoxide acts as a nucleophile by way of the ortho carbon. A small amount of para addition occurs. . . OH COOH salicylic acid + CH 3 COCCH 3 O acetic anhydride H + O OCCH 3 COOH + CH 3 COH aspirin O O CH 3 OH CH 3 OH COOH Quiz 21.04 Provide the missing structures in the scheme below. CH 3 NH 2 (i) NaNO 2 , HBr, H 2 O, 0 o C (ii) Cu 2 O, Cu(NO 3 ) 2 , H 2 O (ii) CO 2 ,pressure, heat (iii) H 3 O + (i) KOH...
View Full Document
This note was uploaded on 10/20/2009 for the course CHEM 322BL at USC.
- Organic chemistry