hw1 - Assignment 1 BIOCHEMICAL CALCULATIONS STRUCTURAL...

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Unformatted text preview: Assignment 1 BIOCHEMICAL CALCULATIONS STRUCTURAL BIOCHEMISTRY CLASS Chem114A/Fall 2009 Due date: WEEK 2 in the middle of your discussion section. Lehninger Chapter 2. Solve Problems: 1 to 28. I z:a1r_ch0 2_041-070 5/Lo/07 3:34 pM page 67 t- I z\rlvancr:<l rt:vicw ol a lrrot.on primll thilt. cmpiovs an int,ernal r:hain of wat.cr rnolcculcs. Nicolls, P. (2()00) itrlroclucl.ion: Lltc bioiog-v of Lhc r,r,at.ur rnolcculc-'. Cell l,[o[. L'ilrt fir.:'i,. 57,987--992. A short rclvic\,v ol Llic propct'l.ics ol wat.cr, int.rochrr:ing scvt.:ral cx- r:c:lk:nt ach,attc:t)rl rr:vir:ws publishcrl in t,irc sarric issuc (sr:t: csllccially Pocker, 20()0, and ltarrl cL al. ,2000, bt:lorv). Symons, M.C. (.20{j0) Sltcctroscolrl, of aqucous solul.ions: protcin an<l IINA in{.erac;l.ions rvith wat,cr. cr:l1,. r{o1,. Li,fe sr;,i,. 5T, ggg-1002. Westhof, E. (ed.) (1993) Wu,tr:r unll iolor1.ir:cr,{, X,lal:'r<nruilr:oules, (lRC Prcss, hrc., Rocii fi,at,on, FL. Fourtr:t-'r-r challLcrs, ear:Lr by il rlii'{clt:nt aur.tror, covcr (al, arr achrancr)cl lcvcl) t,hc struct,rrrc rtf r,vat,cr ancl it,s inl,crar:lirlrs wil,h prot.eins, nuck:i<: ar:icls, polysitc:r;hari<1cs, arul li1iicls. Wiggins, P.M. (199(l) ltole ol'waLcL in sornt-. biological pLocr--sses. il'I'i.r: ru tlt'i.ol. [ier,. 54, 4:]2-4,49 . :\ tcvicw ol'wal,cr in biologv, int:lucling rliscussion oI Lhc plrvsir:al sl.rucLurtt rtf lirluirl wul,er, it,s inl.r:ract.ion rvilh ttiornolct:rrkls, 11cl t.hc: st,itlr. o1 'ur,'at.rtr in living cr:lls. Osmosis Cayley, D.S., Guttman, H.J., & Record, M.T., Jr. (2tXX)) Biopiry.si- t:al characl,t,:rizat,it,rn ol'chiingc.s in anrorurLs ancl ilcl,ivit,y ol' Ilsr:lrcrtr.:lt,iu, r:rtl,'i, r:<:lI:rncl <:omparl.rni:nl wal,cr anri r,urgor pruisulr: in r.t:sllonst: t.ri rrstnr;t.ic st,rcss. B'i,rrytlt 1"y,s.,J. 78, 17,18 .1764. r\n aclvancc<l pirysical inrrcsl,igat.ion ol rhe c:t't,olrlasrnic lr.atcr I|a<:tiotr o1 thc bar:t,ttriurn IIsr:lLr:r"i,r:lLi,rr r.ti.igro\\'lt in iricdia <l{ rlilTer- r:trt. osntolarit,i<:s. (Suc alsrt Rt:t:or<[ i:1. al., lgi_]fJ, br:lor,v.) Rand, R.P., Parsegian, V.A., & Rau, D.C. (2(Xl()) Iut,rac:<.llular os- nrot,ic: act,ion. Ccl,l. Mrtl L,tli:,\r:i. 57, 1018 1L)32. Ikt'u'icrv o{ Lhc rolt:s of rvat.cr in cnzy'urc catal.vsis ils rc\rcilk:cl bv. sl.u< lics in wat,rtr-ltrirtr soluLcs. Record, M.T., Jr., Courtenay, E.S., Cayley, D.S., & Guttman, H.J. (199f3) Rcslx)ttscs of E. rxil:i Lo osmot.ic strcss: largc chiingcs irr arnourrt,s ti['r:l'l,oplasrnic sohrl.cs i-rncl wiil.cr-. Trctrrl,,s [J,i,or.:ltr:rn.. S'r:'i. ZJ. 1,,13 148. InLcrmccliat.c-lttvi:l revit:try ol t,trc \\'a.ys in w'irich a lta<;t,criul cr:il t:oun{,crs r:hangr:s in Lhe osrnolaril,l ol'it.s sun'ounclings. (Sr:c also Oaylr:-v et. al., 2(XX). abovc.) zonia, L., & Munnik, T. (2(x)7) Lilc unrlr:r pressllrt:: h.vrlrostal.ic: pl'cssurc in r;cll gnirvt,h an<l Iirnc:t,ir>n. Trr,trtrls PIu.ttl. ,\r:i," l.z....
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hw1 - Assignment 1 BIOCHEMICAL CALCULATIONS STRUCTURAL...

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