Lec4JCL_W2009 - Bio 305 Lecture 4: Independent assortment,...

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Lecture 4 1 Bio 305 Lecture 4: Independent assortment, meiosis and probability Jan 20, 2009 Dr. Long Required reading: Pre-lecture reading below, including specified book pages Optional further reading: Chapter 3 (p. 89-110) Relevant end of chapter problems: Chapter 3 (1,2, 5, 7-9, 13-15, 17-19, 25-27, 35, 37) Course Pack problems 11-14. Vocabulary: (also see genetic notation for two genes) ascus binomial theorem branching diagrams conditional probability dihybrid dihybrid cross inbreeding independent assortment independent events Mendel's Second Law mutually exclusive events Neurospora octad ordered event parental type product rule (also called Multiplication rule) pure lines recombination recombinant sum rule (also called Addition rule) true-breeding lines unordered events
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Lecture 4 2 Learning Goals: Based on the reading and lecture material from lecture 4, you need to be able to: 1. Describe Mendel's law of independent assortment 2. Use the law of independent assortment to predict genotypic and phenotypic ratios for multiple genes in controlled crosses, including haploids and diploids, autosomal and X- linked genes. 3. Represent multi-gene genotypes with notation that indicates which genes are located on the same and different chromosomes. 4. Describe how true-breeding lines are created from wild isolates. 5. Draw the process of meiosis for multiple chromosomes, labeling the location of different genes and alleles. 6. Indicate which stages during meiosis are responsible for Mendel's first and second laws. 7. Draw the process of meiosis in Neurospora . 8. Identify recombinant and parental types. 9. Use the product rule, sum rule, branching diagrams, binomial theorem and conditional probability to calculate the likelihood (i.e. probability) of ordered, unordered, mutually exclusive, and independent events for both genetic and non-genetic situations.
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Lec4JCL_W2009 - Bio 305 Lecture 4: Independent assortment,...

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