Lecture 9 - RNA Structure Contain ribose instead of...

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RNA Structure Contain ribose instead of deoxyribose A,G,C,U – Uracil pairs with adenine Small chemical difference from DNA, but large structural  differences: Single stranded – ability to fold into 3D shapes
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Ribose and Deoxyribose The sugar moiety of RNA differs from that of DNA. The difference is the presence of a 3’ hydroxyl on the ribose molecule.
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RNA Structure – Types of RNA Messenger RNA (mRNA) – genes that encode proteins Ribosomal RNA (rRNA) – form the core of ribosomes Transfer RNA (tRNA) – the adaptors that link amino acids to mRNA during translation Small regulatory RNA – also called non- coding RNA
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RNA synthesis  RNAP binds, melts     DNA into open form  nucleosides added    5’   3’  so “bottom” strand   is really template
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Promoters The promoter of a gene is defined as the initial RNA polymerase binding site. The transcription start site (defined as nucleotide +1) is close to the promoter and upstream of the start (AUG) codon.
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This note was uploaded on 10/27/2009 for the course BIO 326R taught by Professor Whiteley during the Spring '08 term at University of Texas at Austin.

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Lecture 9 - RNA Structure Contain ribose instead of...

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