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Unformatted text preview: Quaternary
structure
is
present
in
proteins
 with___________________
 A) B) C) D) E) disulfide
bonds
 prosthetic
bonds
 a
modified
N‐terminal
amino
acid
 post‐translational
modification
 none
of
the
above
is
correct
 B) Proteins
that
are
imported
into
the
mitochondrian
 A) interact
with
a
cytosolic
protein
that
 is
required
for
transport
 B) are
synthesized
on
bound
ribosomes
 C) are
synthesized
with
a
signal
 sequence
 D) only
A
and
B
are
correct
 E) A,
B,
and
C
are
correct
 Phospholipids
and
steroids
are
similar
in
that
 A) B) C) D) E) they
are
both
proteins
 they
both
contain
fatty
acids
 they
both
contain
phosphate

 they
are
both
insoluble
in
water
 they
both
contain
a
glycerol
group
 Prior
to
transcription,
DNA
is
 exported
from
the
nucleus
through
 nuclear
pores
 C) Ribosomal
subunits
are
assembled
in
 the
nucleolus,
using
proteins
 imported
from
the
cytosol
 D) DNA
in
the
nucleus
is
organized
into
 a
single
circular
molecule
 E) Ribosomes
are
composed
of
proteins
 that
are
synthesized
on
bound
 ribosomes
 Hydropathy
plots
are
used
to
 A) B) C) D) E) calculate
the
Km
values
for
enzymes
 indetify
signal
sequences
 localize
proteins
within
a
cell
 identify
proteins
that
contain
a
 prosthetic
group
 detect
allosteric
effector
sites
 Some
enzymes
show
allosteric
regulation.
In
such
 cases,
which
of
the
following
would
be
found?
 A) Non‐competitive
inhibition
would
 occur
via
covalent
interactions
 B) Prosthetic
groups
would
be
present
 C) Both
activating
and
inhibitory
 activity
 D) Feedback
inhibition
 E) An
enzyme
with
more
than
one
 subunit
 Which
of
the
following
does
NOT
regulate
the
 activity
of
an
enzyme?
 A) B) C) Post‐translational
modification
 Prosthetic
group
binding
 Substrate‐level
phosphorylaton
 
 D) A,
B,
and
C
are
correct
 E) Only
A
and
B
are
correct
 
I
think
I
told
the
1‐2
discussion
 section
that
the
correct
answer
is
D
but
I
 was
incorrect
(SORRY).

Substrate
level
 phosphorylation
does
not
regulate
 enzyme
activity.
 Put
the
following
events
of
protein
trafficking
 in
order
from
first
to
last.

In
which
part
of
the
 cell
does
each
step
occur?
 o Protein
is
glycosolated
(5)
 o Signal
recognition
particle
binds
 to
protein
(2)
 o Protein
is
transported
to
the
 lysozome
(8)
 o Ribosome
is
released
from
 protein
(4)
 o Sugars
are
selectively
cleaved
 from
the
protein
(6)
 Autotrophic
prokaryotes
contain

 A) B) C) D) E) chlorophasts
 and
endomembrane
system
 ribosomes
 mitochondria
 more
than
one
chromosome
 Proteins
secreted
from
the
cell…
 A) B) are
transported
in
vesicles
 are
fully
synthesizes
on
free
 ribosomes
 C) undergo
post‐translational
 modification
 D) only
A
and
C
are
correct
 E) A,B,
and
C
are
all
correct
 Peroxisomes
contain
proteins
that

 A) B) C) are
coded
for
by
nuclear
genes
 are
modified
in
the
rough
ER
lumen
 are
synthesized
on
cytosolic
 ribosomes
 D) 
A
and
C
are
correct
 E) B
and
C
are
correct
 Which
of
the
following
statements
is
true?
 A) The
nucleus
contains
ribosomes
and
 synthesizes
some
of
its
own
proteins
 within
the
organelle

 
 
 If
given
the
amino
acid
sequence
of
a
protein
how
could
you
determine
if
this
protein
could
be
found
within
the
 plasma
membrane?

 ANSWER:

A
hydropathy
plot
could
be
used
to

help
determine
if
the
protein
of
interest
is
a
membrane
bound
 protein
 
 
 
 How
are
the
kinetics
of
facilitated
diffusion
across
a
membrane
and
enzyme
activity
similar?
Why
are
they
 similar?
 
 ANSWER:
The
kinetics
of
facilitated
diffusion
across
a
plasma
membrane
and
enzyme
activity
are
similar
 because
they
both
have
saturation
curves
which
symbolized
the
saturation
of
the
sites
of
interaction
for
each
of
 the
respective
molecules
(Enzymes:
all
of
the
active
sites
are
saturated
with
substrate;
facilitated
diffusion
all
of
 the
transport
proteins
are

 
 
 
 The
following
reaction
requires
enzyme
Bearase
for
function.

 
 
 
 
 A+B
C
 You
find
that
by
adding
small
molecule
“X”
you
decrease
the
Km
of
the
overall
reaction.
What
is
the
role
of
X
in
 the
reaction?
 
 ANSWER:
Since
you
need
less
substrate
to
reach
½
Vmax

molecule
X
increases
the
efficiency
of
the
enzyme;
X
 acts
as
an
activator.

 
 
 
 You
also
find
that
molecule
“T”
increases
the
Km
of
the
reaction.
What
is
the
role
of
T
in
the
reaction?
 
 ANSWER:
Since
you
need
more
substrate
to
reach
½
Vmax
molecule
T
inhibits
the

activity
of
the
enzyme.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 o o Ribosome
attaches
to
an
RNA(1)
 Protein
enters
ER
(3)
 o Protein
binds
to
a
receptor
in
a
 transport
vesicle
(7)
 ...
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This note was uploaded on 10/29/2009 for the course BIO biology taught by Professor Meighan during the Fall '09 term at University of California, Berkeley.

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