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Unformatted text preview: 3. The energy stored in the myosin is released as the myosin pulls on the actin fiber. 4. At the same time the ADP is released from the myosin exposing an ATP binding site. 5. ATP binds to the myosin. 6. The actin/myosin bond is broken with myosin returning to its relaxed state. 7. The attached ATP is hydrolyzed recharging the myosin. 8. If it can, the myosin binds to the actin returning to number 3 above. The cycle continues as long as actin and myosin can bind which depends on Ca++ being bound to troponin (i.e. the level of free calcium remains high). Note that in the absence of ATP, the actin/myosin bond cannot be broken. This is the cause of Rigor Mortis....
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This note was uploaded on 11/01/2009 for the course BIO 3110 at Cornell University (Engineering School).