311C F09 Worksheet_7+A - NAME _ Discussion Worksheet #7...

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NAME ____________________________ Bio 311C Discussion Worksheet #7 Cell Communication 1. What determines which cell(s) will be bound by a ligand? LIGAND WILL ONLY BIND CELLS THAT HAVE THE CORRECT/SPECIFIC RECEPTOR FOR THAT LIGAND. 2. Describe one difference between a ligand for an intracellular receptor and a ligand for an extracellular receptor. INTRACELLULAR: SMALL & HYDROPHOBIC; MUST PASS THROUGH MEMBRANE EXTRACELLULAR: CAN BE LARGE & WATER SOLUBLE; DON’T HAVE TO PASS THROUGH 3. In general what happens to a receptor protein when it binds a ligand? UNDERGOES SOME SORT OF CHANGE OR ACTIVATION - TYPICALLY A CONFORMATIONAL CHANGE. 4a. List one difference between paracrine signaling and endocrine signaling. PARACRINE ENDOCRINE LOCAL SIGNALING (SHORT DISTANCE) LONG DISTANCE SIGNALING USES LOCAL REGULATORS (GROWTH FACTORS) USES HORMONES 4b. List one similarity between paracrine signaling and endocrine signaling. BOTH REQUIRE THE SECRETION OF SIGNAL THAT CAN BE RECEIVED BY MULTIPLE TARGET CELLS.
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311C F09 Worksheet_7+A - NAME _ Discussion Worksheet #7...

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