ch08 - Which of the following is true about mutations in...

Info iconThis preview shows pages 1–16. Sign up to view the full content.

View Full Document Right Arrow Icon
Which of the following is true about mutations in DNA? A. Deamination and depurination are always caused by chemical agents. B. DNA damage caused by reactive chemicals and energy-rich radiation results in mutations because cells have no DNA repair systems. C. Deamination occurs spontaneously under normal physiological conditions. D. Depurination results in the cleavage of the bond between the base and the phosphate.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Nucleotides and Nucleic Acids Chapter 8
Background image of page 2
8-1 What kind of ring is this? furanose General structure of a nucleotide
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
8-2
Background image of page 4
8-4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
8-3b The ribose ring structure is puckered
Background image of page 6
1 9 8-4 Is this bond α or β ? always β N-glycosidic bond
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
8-5 Modified bases in DNA and RNA
Background image of page 8
8-7 Nucleic acid polymers
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Why is DNA resistant to base-hydrolysis? 8-8 Lacks 2’-OH - can’t form cyclic intermediate Base hydrolysis of RNA
Background image of page 10
8-10 Chemistry of aromatic bases -- absorb UV light near 260 nm
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Tautomeric conversions of bases 8-9 Where are the H-bond donors and acceptors for guanine tautomers? donor acceptor donor acceptor
Background image of page 12
8-11 Base pair hydrogen bonding
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
DNA structure 2003 = 50 th anniversary of discovery of structure of DNA by Watson and Crick. Avery-MacLeod-McCarty experiments with pneumococcus (1944) and Hershey-Chase experiments with bacteriophage (1952) convinced most scientists that DNA was the genetic material…
Background image of page 14
analyzed DNA composition from many organisms and tissues and concluded these rules: 1. base composition varies from species to species, but is the same in different tissues of same species
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 16
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 50

ch08 - Which of the following is true about mutations in...

This preview shows document pages 1 - 16. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online