ch11 - The hydrolysis of nucleoside triphosphates(NTPs A.is...

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The hydrolysis of nucleoside triphosphates (NTPs) A. is required for them to act as regulatory molecules. B. is needed for their function as cofactors. C. allows for hydrogen bonding of double-stranded DNA. D. provides the chemical energy needed for some biochemical reactions.
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1 9 8-4 Is this bond or ? always N-glycosidic bond
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8-27 Why does melting point of DNA increase with more G+C? 3 H-bonds vs. 2 for A-T DNA melting can be monitored by UV absorption which increases with temp ( hyperchromic effect ).
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Which of the following is true about motion of membrane lipids? A. They can move most rapidly when in the gel phase. B. Lateral diffusion is catalyzed by flippase proteins. C. To increase the fluidity of membranes at low temperatures, cells synthesize more saturated fatty acids and fewer unsaturated fatty acids. D. Transbilayer (flip-flop) diffusion involves the transfer of lipids from one face of the bilayer to another.
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Membranes and Transport Chapter 11 What does it take for a cell to be “alive”? Integrity of compartment Energy Respond to environment Reproduce itself
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11-3 Lipid Bilayer
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11-4 What force drives lipids into these structures? Hydrophobic interactions 2 x 15 = 30 Å ~20-30 Å Total thickness ~50-60 Å (5-6 nm) Membrane lipids = amphipathic molecules
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Bilayer is a two-dimensional fluid 11-16
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Why is this slow compared with lateral diffusion? Very difficult to pass hydrophilic head group through hydrophobic interior of bilayer 11-16
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How do you think these enzymes work? Probably provides a hydrophilic path for the polar head group through hydrophobic interior of bilayer 11-16
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11-15 Low temp High temp Membrane fluidity
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11-19 Membrane proteins also diffuse laterally unless anchored to cytoskeleton
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Bilayer is asymmetrical: lipid asymmetry 11-5
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11-3 Bilayer is asymmetrical: protein asymmetry
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Membrane proteins Basic structure of membranes
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