042309homework

042309homework - Homework due 4/23/09 Name _ 1. Draw a...

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Homework due 4/23/09 Name _______________________________ 1. Draw a dopamine synapse and label the various dopamine receptors that exist. Also show the dopamine transporter and an axoaxonic synapse. What POTENTIALLY could go wrong to cause dopamine over-activity in the synapse. What do we know is going wrong? How is it treated? 2. Describe the updated model of how the malfunctioning of dopamine synapses might give rise to the positive and negative symptoms of schizophrenia. How does this help explain the limited effectiveness of the typical antipsychotics? 3. What are the typical and atypical antipsychotics. Where in the synapse are they thought to exert their effects? Describe some important clinical side effects of both classes of antipsychotics? Since the atypical antipsychotic more effectively treat the broad spectrum of schizophrenic symptoms and don’t cause extrapyramidal side effects why aren't they used exclusively?
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4. Describe the reciprocal interactions between glutaminergic and dopaminergic
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042309homework - Homework due 4/23/09 Name _ 1. Draw a...

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