Bio Forces of Evolution Notes - Evolutionary Forces Text...

Info iconThis preview shows pages 1–14. Sign up to view the full content.

View Full Document Right Arrow Icon
Evolutionary Forces Text © Kurland, 2005
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Mutation Mutagens: mutation inducing agents: ionizing radiation, chemicals, … Random!
Background image of page 2
Point Mutation: Base-Pair substitutions Errors: DNA synthesis/repair EX: Sickle-Cell Anemia (More Later)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Original DNA: AAA TTT CCC Phe Lys Gly Deletion: AAT TTC CC_ Leu Lys
Background image of page 4
Original DNA: AAA TTT CCC Phe Lys Gly Insertion: ACA ATT TCC C_ _ Cys Stop Arg
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Original DNA: AAA TTT CCC Phe Lys Gly Inversion: AAT TTA CCC Leu Asp Gly
Background image of page 6
Neutral Mutation = Most Mutations! CAA CAT Val Val
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Ancestry: Europe Genetics: short arm, Chromosome 3 DNA Site: 3p21 32 base-pair deletion Frequency: p 14%, Africa = 0% Evolution: Deletion Bubonic Plague, Smallpox Epidemics Our Friend, Mutation: HIV AIDS & CCR5- 32
Background image of page 8
Chromosome # Change: Translocation (Insertion), Inversion, Deletion Aneuploidy: 2N 4N, 6N … Meiotic Error = Non-Disjunction EX: Down Syndrome, Trisomy 21, 2n = 47
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Cognitive Impairment, Autism “Mongolian” eyes = upward slant Unique ear shape Cardiac defects Life-Expectancy: +50 Bioethics: Rearing or Elective Abortion? Down Syndrome, Trisomy 21
Background image of page 10
Ancestry: ? Genetics: Trisomy (90%) Translocation (10%) Chromosome 21 Prevalence: 1/900 (0.11%) Birth Evolution: Chromosomal Mutation NB: β - Amyloid on Chromosome 21 Alzheimer’s Disease
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Gene Duplication: Unequal Crossing-Over Repeat short sequence of DNA Creation of new genes Modularity EX: Globin Gene Family, Haemoglobin
Background image of page 12
Neutral/Deleterious/Beneficial
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 14
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/03/2009 for the course ANTH 021 taught by Professor Ratcliffejeffrey during the Fall '08 term at Pennsylvania State University, University Park.

Page1 / 35

Bio Forces of Evolution Notes - Evolutionary Forces Text...

This preview shows document pages 1 - 14. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online