Lecture-14 - Key Concepts: I. Neuronal Membrane Potential...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
Key Concepts: I. Neuronal Membrane Potential II. Action Potentials and how they are generated III. Neurotransmitters IV. Metabotrophic vs Ionotropic Receptors V. Properties of Ionotropic Receptors VI. Cys-loop vs Glutamate Receptors VII. Single Channel Properties VIII. Benzodiazepines vs Barbiturates
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Neurons at REST have high levels of intracellular K + . An Action Potential is generated when a stimulus, such as NEUROTRANSMITTER binding, causes an exchange of ions across the membrane.
Background image of page 2
The action potential travels down the axon and causes neurotransmitter release. This is chemical neurotransmission.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
But wait… what are neurotransmitters again? Neurotransmitters are small molecules released by neurons which bind receptors on the post-synaptic cell. Dopamine Serotonin Glutamate GABA Acetylcholine
Background image of page 4
What do neurotransmitters do? Excitatory postsynaptic potentials ( EPSPs ) increase the likelihood of action potential generation in the postsynaptic cell (increases membrane potential). Inhibitory PSPs ( IPSPs ) decrease the likelihood of action potential generation (decrease membrane potential).
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Nature of postsynaptic cell’s response to neurotransmitter depends on: the
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/04/2009 for the course BIO 365D taught by Professor Mihic during the Spring '08 term at University of Texas at Austin.

Page1 / 20

Lecture-14 - Key Concepts: I. Neuronal Membrane Potential...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online