Lecture-22 - Carcinogenesis What are your chances of...

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Carcinogenesis What are your chances of developing some sort of cancer in your lifetime? A. 1 in 1000? B. 1 in 100? C. 1 in 20? D. 1 in 10? E. 1 in 3?
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Incidence and mortality from cancers rises with age. Most (60-90%) of cancers are primarily due to environmental factors (nongenetic factors including diet, environmental chemical exposure, cultural and behavioural practices). One third (!!) of all cancer deaths in North America are related to the use of tobacco products . Most mortality rates from cancers have either remained constant or declined during the 20th century except. ..
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Men Women Cancer mortality rates Increases in lung cancer incidence reflect the long latency period of cancer development.
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Many cancers may not become evident for 10-20 years after exposure to the responsible agent, making it more difficult to ascribe responsibility for the cancer to any particular environmental agent. Both natural and synthetic compounds can be carcinogenic.
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Even cancer fighting drugs can be carcinogenic. ..
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Don’t panic! Most compounds are NOT carcinogenic. Okay, panic a little bit. Most chemicals have not been tested adequately for their carcinogenicities.
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Carcinogens come from a wide variety of chemical classes, so there is no simple structure-activity rule that
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This note was uploaded on 11/04/2009 for the course BIO 365D taught by Professor Mihic during the Spring '08 term at University of Texas at Austin.

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Lecture-22 - Carcinogenesis What are your chances of...

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