Lecture-32 - Drugs of abuse: pot, speed, crack, acid and...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Cannabis The hemp plant ( Cannabis sativa ) produces a number of chemically related compounds of which 1- 9-tetrahydrocannabinol is the primary active ingredient. The dried leaf material is marijuana (or grass, pot, ganja, bhang, etc. ..). 9 -THC is found in the resinous material coating immature flowering tops and in leaves. The resinous material is hashish and it has 5-10 times as much 9 -THC as marijuana. In the past 20 years the 9 -THC content in pot has increased from 1% to 3-4% and some carefully selected and cloned plants can yield 15%. THC is very lipophilic, is absorbed rapidly through alveolar membranes, and has a half life of elimination in humans of about two days. Drugs of abuse: pot, speed, crack, acid and XTC
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Pharmacological effects of cannabis Increase in heart rate Sharpened sensory acuity and more α rhythm in EEG . Thinking is slowed and impaired as is short-term memory Emotional lability and relaxation In humans, THC impairs motor performance (eg. driving) and its effects are at least additive with alcohol. High doses can produce distortions in time & space perception, auditory & visual hallucinations, even acute psychotic episodes.
Background image of page 2
Mechanism of action of THC Binds specifically to CB cannabinoid receptors that are
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
1. Chronic bronchitis & increased bronchopulmonary cancer rates in heavy smokers. 1. Amotivational syndrome (mental slowing, loss of memory and drive, difficulty with abstract concepts, flat affect). Signs may remain after use is discontinued - organic brain damage? 1. Chromosomal damage, impaired immune response
Background image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/04/2009 for the course BIO 365D taught by Professor Mihic during the Spring '08 term at University of Texas at Austin.

Page1 / 12

Lecture-32 - Drugs of abuse: pot, speed, crack, acid and...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online