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Unformatted text preview: number is required to prevent any supercoiling during transcription? (You can assume that there are 10 bp per Watson-Crick helical repeat). 4. If, starting with a fully base-paired, non-supercoiled pBR322 DNA, topoisomerase II is used to relax the supercoiling caused by the transcription in problem #5, how many ATPs would be consumed? 5. What are the functions of the following in DNA replication? DNA ligase 3'-exonuclease of DNA polymerase III DNA gyrase SSB Primase _ subunit of DNA polymerase III DNA polmerase I Okazaki fragments 6. Why must eukaryotic chromosomes end in telomeres?...
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This note was uploaded on 11/07/2009 for the course BIOCHEM bIO taught by Professor Professor during the Spring '09 term at École Normale Supérieure.
- Spring '09