Mendel 4 - Mechanisms of Inheritance IV X chromosome H...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Mechanisms of Inheritance IV X chromosome, H. sapiens Road Map to Today • Apparent violations of Mendelian genetics: – Sex linked traits, incomplete dominance, pleiotropy, polygeny & epistasis, continuous traits • Multiple traits: Dihybrid crosses • Linkage & Gene mapping Complications: Sex-linked traits
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 Complications: Sex-linked traits X, y X, x XX, Xx, Xy, xy Complications: Sex-linked traits Complications: Sex-linked traits
Background image of page 2
3 Complications: Sex-linked traits • Unexpectedly large proportion of males exhibiting trait, IF recessive: – Colorblindness, haemophilia, X-linked severe combined immunodifficiency, etc • Can be dominant: – Vitamin-D resistent ricketts Complications: Dominance is not the rule… Ooops… blended trait? Is it still Mendelian inheritance? Complications: Dominance is not the rule… • Incomplete dominance
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 Complications: Pleiotropy • More than one trait determined by a gene Complications: Pleiotropy Marfan syndrome: • Dominant allele on chromosome 15 • Deficiency in fibrillin, essential for connective
Background image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/08/2009 for the course HUMBIO 2A taught by Professor Boggs,c;durham,w during the Spring '08 term at Stanford.

Page1 / 13

Mendel 4 - Mechanisms of Inheritance IV X chromosome H...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online