Molecular Genetics 4

Molecular Genetics 4 - Molecular genetics IV 10/29/08...

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Molecular genetics IV 10/29/08 Francke 4 1 10/28/08 HumBio2A: Molec. Genetics IV converts RNA sequence to polypeptide sequence 1. The Genetic Code 2. tRNAs, ribosomes, and process of protein synthesis 3. What happens to proteins after translation Molecular Genetics IV RNA to protein: Translation Figure 12.2 The Central Dogma Complementary mRNA Protein DNA Information flows in one direction when genes are expressed The Central Dogma 10/28/08 HumBio2A: Molec. Genetics IV The Central Dogma DNA RNA protein The Watson-Crick structure suggested a means to translate the genetic code (genotype) to protein (phenotype) Q P L M C D T Note the colinearity of the DNA sequence and the amino acid sequence
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Molecular genetics IV 10/29/08 Francke 4 2 10/28/08 HumBio2A: Molec. Genetics IV The genetic code : specifies which amino acids will be used to build a protein Codon : a sequence of three bases. Each codon specifies a particular amino acid. Start codon : AUG—initiation signal for translation Stop codons : stops translation and polypeptide is released
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This note was uploaded on 11/08/2009 for the course HUMBIO 2A taught by Professor Boggs,c;durham,w during the Spring '08 term at Stanford.

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Molecular Genetics 4 - Molecular genetics IV 10/29/08...

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