EvoDevoCH25

EvoDevoCH25 - 9/21/2009 EvoDevo: Evo-Devo Evolutionary...

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9/21/2009 1 Evo Devo: Evolutionary Developmental Biology and the Form of New Species Evo-Devo ± Evolutionary developmental biology ± Compares the development of different organisms in an attempt to understand ancestral relationships between organisms and the developmental mechanisms that bring about evolutionary change ± Involves the discovery of genes that control development 2 Developmental genes are key players in evolution ± Changes in developmental genes affect traits that can be acted on by natural selection ± Compare chicken and duck foot ² Due to differences in expression of 2 cell- signaling proteins ± BMP4 – causes cells to undergo apoptosis and die ± Gremlin – inhibits the function of BMP4 and allows cell to survive 3 4 ± Mutations on the expression of BMP4 and gremlin provided variation ± In terrestrial settings, nonwebbed feet are an advantage ² Natural selection maintains nonwebbed feet ± In aquatic environments, webbed feet are an advantage ² Natural selection would have favored webbed feet ± Speciation may have been promoted by geographical isolation of habitats 5 Hox genes ± Found in all animals ± Genetic variation may have been critical event in the formation of new body plans ± Number and arrangement of Hox genes varies among different types of animals ± Increases in the number of Hox genes may have led to greater complexity in body structure 6
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9/21/2009
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EvoDevoCH25 - 9/21/2009 EvoDevo: Evo-Devo Evolutionary...

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