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Concept 9 - Concept9.3: InthepresenceofO2,...

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Concept 9.3: The citric acid cycle completes the energy-yielding oxidation of organic molecules In the presence of O 2 , pyruvate enters the mitochondrion Before the citric acid cycle can begin, pyruvate must be converted to  acetyl CoA , which links the cycle  to glycolysis  Pyruvate from cytosol enters the mitochondria by active transport Pyruvate > acetyl CoA  The citric acid cycle, also called the Krebs cycle, takes place within the mitochondrial matrix The cycle oxidizes organic fuel derived from pyruvate, generating 1 ATP, 3 NADH, and 1 FADH 2  per  turn 2 turns per 1 original glucose molecule  The acetyl group of  acetyl CoA  joins the cycle by combining with  oxaloacetate , forming  citrate The next seven steps decompose the citrate back to oxaloacetate, making the process a cycle The NADH and FADH 2
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