NPB%20112%2009%20Sample%20midterm%201%20_1%20_93_

NPB%20112%2009%20Sample%20midterm%201%20_1%20_93_ - NPB 112...

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1 NPB 112, FALL 1993 MIDTERM # 1 ______________ ___________ Name SS Number MULTIPLE CHOICE QUESTIONS. 2 points each. Write letter of correct answer in blank. If a question is unclear, check box at top of page and explain on back. ___ 1. Hodgkin, Huxley, Katz and Eccles had what in common: a. collaborated to develop the patch clamp method b. each contributed to understanding the function of the cerebral cortex c. each won a Nobel Prize for work in cellular neurophysiology d. were all born in Australia ___ 2. Stimulating a presynaptic neuron in low Ca++ medium evokes postsynaptic depolarizing responses that are multiples of 0.3 mV. What is the minimum number of synaptic vesicles that must release their contents to produce an EPSP of 3 mV at this synapse in a normal Ca++ medium? ___ 3. During synaptic transmission, Ca++ does NOT do which of the following: ___ 4. An axon in the nerve of an alien from another planet has concentrations of ions X+ and Y- that are 100 times higher on the outside than the inside of the axon. It has concentrations of Z+ and A- that are 100 times higher on the inside than the outside of the axon. At rest, the axon membrane is highly permeable to Z+ and only slightly permeable to X+. The resting membrane potential of this axon is: (a) 0 (b) more positive than 0 (c) more negative than 0 ___ 5. For the alien axon from the preceeding question #4, what are the respective directions of the chemical driving force (due to concentration difference) and electrical driving force (due to electrostatic interaction) on X+: (a) chemical inward (toward the inside of the axon); electrical outward (b) chemical outward; electrical inward (c) chemical and electrical both inward (d) chemical and electrical both outward
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