NPB%20112%2009%20Sample%20midterm%201%20_1%20_93_ - NPB 112...

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1 NPB 112, FALL 1993 MIDTERM # 1 ______________ ___________ Name SS Number MULTIPLE CHOICE QUESTIONS. 2 points each. Write letter of correct answer in blank. If a question is unclear, check box at top of page and explain on back. ___ 1. Hodgkin, Huxley, Katz and Eccles had what in common: a. collaborated to develop the patch clamp method b. each contributed to understanding the function of the cerebral cortex c. each won a Nobel Prize for work in cellular neurophysiology d. were all born in Australia ___ 2. Stimulating a presynaptic neuron in low Ca++ medium evokes postsynaptic depolarizing responses that are multiples of 0.3 mV. What is the minimum number of synaptic vesicles that must release their contents to produce an EPSP of 3 mV at this synapse in a normal Ca++ medium? (a) 1 (b) 10 (c) 100 (d) 1,000 ___ 3. During synaptic transmission, Ca++ does NOT do which of the following: (a) disengage synaptic vesicles from actin filament cytoskeleton (b) promote binding of synaptic vesicle to docking protein in terminal membrane (c) inhibit movement of synaptic vesicles toward the terminal membrane (d) promote exocytotic release of transmitter from synaptic vesicle ___ 4. An axon in the nerve of an alien from another planet has concentrations of ions X+ and Y- that are 100 times higher on the outside than the inside of the axon. It has concentrations of Z+ and A- that are 100 times higher on the inside than the outside of the axon. At rest, the axon membrane is highly permeable to Z+ and only slightly permeable to X+. The resting membrane potential of this axon is: (a) 0 (b) more positive than 0 (c) more negative than 0 ___ 5. For the alien axon from the preceeding question #4, what are the respective directions of the chemical driving force (due to concentration difference) and electrical driving force (due to electrostatic interaction) on X+: (a) chemical inward (toward the inside of the axon); electrical outward (b) chemical outward; electrical inward (c) chemical and electrical both inward (d) chemical and electrical both outward ___ 6. The EPSP (a) is a depolarization of the postsynaptic membrane (b) is caused by neurotransmitter binding to postsynaptic receptors (c) is due to Na+ influx through non-selective ion channels that also allow K+ efflux (d) all of the above are correct ___ 7. If the quadraceps (thigh) muscle were rapidly stretched by tapping the knee tendon, which response would be recorded intracellularly from a motor neuron to an antagonist (hamstring) muscle: (a)
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This note was uploaded on 11/14/2009 for the course NPB 33042 taught by Professor Carstens during the Spring '09 term at UC Davis.

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NPB%20112%2009%20Sample%20midterm%201%20_1%20_93_ - NPB 112...

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