M2 lecture 1

M2 lecture 1 - 1 NPB 112, Fall 2009 10-29-09 I. Cerebellum...

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Unformatted text preview: 1 NPB 112, Fall 2009 10-29-09 I. Cerebellum and basal ganglia: Ch. 18, 19 A. functions of cerebellum (Ch. 19): 1. Maintains equilibrium and stance. 2. correct ongoing movements. 3. Initiation of movement. 4. Learns and stores motor programs. 5. Timing function (like a clock)? 6. cognition? (e.g., language processing) B. Deficits due to cerebellar damage: 1. vestibulocerebellum: loss of equilibrium, wide stance, fall over, and "drunken sailor's gait" = ataxia 2. spinocerebellum damage: loss of fine coordination. a. Decomposition of movement: complex motor act performed as succession of parts; becomes disjointed or fractionated. Movements are no longer smooth, but must be consciously reconstructed by consciously piecing together the various components. b. Reduced ability to correct ongoing movement. (1). over- or undershoot of target (dysmetria) (2). deficit in timing (disdiochokinesia): can't perform rhythmically alternating movement pattern (3). Slurred speech (dysarthria) 3. lateral cerebellum a. loss of learned motor skills such as playing musical instrument. b. Delayed reaction time. c. Functional recovery following damage (better when young). II. Functional organization of cerebellum (Ch. 19) A. Functional divisions of cerebellum (Fig. 19.1 (A)): 1. vestibulocerebellum (medial) = posture. Deep cerebellar nucleus = fastigial 2 2. spinocerebellum = coordination (thread needle). Deep nucleus = interposed 3. lateral (cerebro-) cerebellum = planning and storing programs. Deep...
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M2 lecture 1 - 1 NPB 112, Fall 2009 10-29-09 I. Cerebellum...

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