2008 M1 - 1 BIS 101 002 MIDTERM I ANSWER KEY 2 Name Page 3...

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1 BIS 101 - 002 MIDTERM I April 24, 2008 ANSWER KEY
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2 Name:______________________________ P a g e : 3 ________ 4 ________ 5 ________ 6 ________ 7 ________ 8 ________ Total ________ Bonus_________
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3 Name:______________________________ ( 1 ) For each pedigree shown below, determine the most probable mode of inheritance: autosomal recessive, autosomal dominant, X-linked recessive, X-linked dominant, Y- linked. (4 points each) (A) Autosomal recessive (B) X-linked recessive (C) Autosomal dominant (2) In a population of mice, there are two alleles of the A locus ( A 1 and A 2 ). Tests showed that in this population there are: 384 mice of genotype A 1 /A 1 210 mice of genotype A 1 /A 2 260 mice of genotype A 2 /A 2 _____ 854 What are the frequencies of the two alleles in the population? (6 points) 2 x 384 + 210 978 f( A 1 ) = _____________________ = _________________ = 0.57 2 x 854 1,708 2 x 260 + 210 730 f( A 2 ) = _____________________ = _________________ = 0.43 2 x 854 1,708
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4 Name:______________________________ (1) The pedigree below was obtained for a very rare disease. Assume that individuals marrying into the family are homozygous normal. If individuals 1 and 2 marry, what is the probability that their first child will have the disease? Indicate the genotypes of all relevant individuals in the pedigree. (8 points) Probability of individual 1 to be a heterozygote is 1/2. Probability of individual 2 to be a heterozygote is 1. Probability of their first child to have the disease is therefore 1/2 x 1 x 1/4 = 1/8 (1) A plant of genotype AaBbCcDdEe was selfed. Alleles A, B, C, D, and E are completely dominant over alleles a, b, c , d, and e respectively. The
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This note was uploaded on 11/14/2009 for the course NPB 33042 taught by Professor Carstens during the Spring '09 term at UC Davis.

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2008 M1 - 1 BIS 101 002 MIDTERM I ANSWER KEY 2 Name Page 3...

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