Study Guide Chapter 28 - requirements. 6. Describe...

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Chapter 28: DNA Replication, Recombination and Repair Review Questions 1. Describe the characteristics of the B form DNA and explain how it differs from A and Z forms of DNA. 2. Explain the concept of Topoisomers of DNA. Explain in terms of Lk, Tw and Wr. 3. In what respect does Topoisomerase I and Topoisomerase 11 (DNA gyrase) differ in their mechanism of action? 4. Write the reaction catalyzed by the enzyme, DNA ligase. 5. Describe the steps involved in the replication of DNA. How does the synthesis of the leading and lagging strands differ? Include the names of enzymes and, other
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Unformatted text preview: requirements. 6. Describe transition and transversion as it pertains to DNA mutation. 7. Describe how mutation of a DNA base alters the genetic code during DNA replication with specific examples. 8. What is a thymine-dimer? Explain how a thymine dimer is repaired. 9. Explain why thymine rather than uracil is selected to carry genetic information in DNA. 10. Describe the basis of Ames test to screen environmental mutagens. 11. Describe the structural organization of a nucleosome. Be specific....
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