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Unformatted text preview: Chapter 12 Mitosis (division of the nucleus) • mitosis is involved in cell divisions that increase cell number for reproduction (single celled organisms), growth and repair • the cells before and after mitosis are genetically identical • review the stages of mitosis by drawing diagrams • review the experiment that showed how the spindle moves cells to the poles Regulation of the Cell Cycle • know the phases [G1, (G0) S, G2, M] and checkpoints • internal control – MPF (cyclin and CDK) • cyclin levels vary during the cell cycle • cyclin dependent kinase (cdk) levels are constant • MPF is a complex of cyclin and cdk that promote mitosis – APC • causes sister chromatids to ‘unzip’ • external control – growth factors • cancer – often involves abnormalities of the cell cycle – properties of cancer cells...
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This note was uploaded on 11/18/2009 for the course BIO 113 taught by Professor Swenson during the Spring '08 term at Ohio State.
- Spring '08