pathology

pathology - Which of the following cells are important in...

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Unformatted text preview: Which of the following cells are important in an innate immune response to extracellular bacteria? QID: 2635 Click in the circle next to your answer choice A. T lymphocytes B. B lymphocytes C. Neutrophils D. Eosinophils E. Mast cells The answer is: C Innate immunity involves antigen-nonspecific immune defense. Neutrophils circulate in the blood and can migrate into tissue to ingest and kill bacteria. Although T and B cells can augment the innate immune response, they become inactivated in an antigen-specific manner. Eosinophils, also part of the innate immune response, are important in parasitic, rather than bacterial, infections 2. Which one of the following is the most potent and effective antigen-presenting cell (APC)? Click in the circle next to your answer choice A. Monocytes-macrophages B. Mast cells C. T lymphocytes D. B lymphocytes E. Dendritic-Langerhans cells answer is: E Dendritic/Langerhans cells are the most potent and effective antigen-presenting cells (APC). The other cells do not possess as effective an antigen-presenting capability 3 To determine whether a fetus acquired an infection in utero, antigen-specific antibody to which of the following classes should be measured? Click in the circle next to your answer choice A. IgA B. IgM C. IgG D. IgD E. IgE answer is: B The fetus and newborn infant can only produce measurable IgM antibody in response to infection. If IgG is detected, it is the result of an immune response by the mother and the antibody has crossed the placenta 4. Which one of the following complement components mediates cytolysis? Click in the circle next to your answer choice A. C1 B. Factor B C. C3b D. C5a E. C5b6789 answer is: E Complement components C5b, 6, 7, 8, and 9 associate to generate the membrane attack complex (MAC) that disrupts the integrity of the cell membrane on which it is formed. 5. Which one of the following complement components is a chemoattractant for neutrophils? Click in the circle next to your answer choice A. C1 B. Factor B C. C3b D. C5a E. C5b6789 answer is: D Several complement cleavage products promote inflammatory responses: C3a, C4a, and C5a. They can also induce the degranulation of mast cells and so are also referred to as anaphylatoxins. C5a has the additional property whereby it is a neutrophil- chemoattracting substance 6. A 6-year-old boy has received a deep puncture wound while playing in his neighbor's yard. His records indicate that he has had the standard DPT immunizations and a booster when he entered school. What is the most appropriate therapy for this child? A. Tetanus toxoid B. Tetanus antitoxin C. Both toxoid and antitoxin at the same site D. Toxoid and antitoxin at different sites E. No treatment answer is: E Because the boy received his booster within the last 2 years, his level of immunity should be adequate. If an individual has no history of immunization, both antitoxin (passive immunization with tetanus immune globulin) for temporary and fast protection and toxoid (toxin detoxified with formaldehyde) for future and long-lasting protection should...
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This note was uploaded on 11/21/2009 for the course BIO 1B taught by Professor Carlson,mischel,power during the Summer '07 term at Berkeley.

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pathology - Which of the following cells are important in...

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