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Unformatted text preview: Last few pathology questions. Possible repeats. Missing probably 50 ?’s from website after this 20. Which of the following is seen most commonly in association with primary biliary cirrhosis (PBC)? A. Positive antinuclear antibody (ANA) B. Increased ceruloplasmin C. Increased ferritin D. Positive hepatitis B surface antigen E. Positive antimitochondrial antibody (AMA) The answer is: E Positive AMA is seen in approximately 95% of primary biliary cirrhosis (PBC) patients. ANA is seen in a few patients. Decreased ceruloplasmin and increased ferritin levels are usually seen in Wilson's disease and hemochromatosis, respectively. There is no association between Hepatitis B surface antigen and PBC 21. Previously, you treated a 44-year-old man, a former intravenous drug abuser, for acute hepatitis C infection. Several months later, it is clear that the patient has chronic hepatitis and may need therapy with interferon. Which long-term complications of hepatitis C infection must you discuss so that the patient can make an informed decision about treatment? A. Hepatoma and cirrhosis B. Hepatic adenoma C. Sclerosing cholangitis D. Hemochromatosis E. Lymphoma or leukemia The answer is: A The most serious consequences of chronic hepatitis B and C infections are hepatoma and cirrhosis. Complications of cirrhosis may occur, resulting in liver failure. Chronic hepatitis is not a risk factor for adenoma, cholangitis, lymphoma, or hemochromatosis 22. Fatigue, anorexia, orange/brown-colored urine, and an ALT level greater than 10 times normal are clinical features of which of the following A. Hepatitis A B. Any viral hepatitis C. Hepatoma D. Hepatitis B and hepatitis C E. Hepatitis B, but not hepatitis C The answer is: B Acute viral hepatitis, no matter what the etiology, usually presents in a similar manner with fatigue and anorexia, malaise, and dark-colored urine, if jaundice is present. The transaminases, AST and ALT, are usually elevated 10 times above normal levels 23. Protective vaccines are available for which of the following hepatitis viruses? A. A and B B. A and D C. A and C D. B and C E. C and D The answer is: A Currently, protective vaccines are available for hepatitis A (2 doses 6 months apart) and hepatitis B (3 doses; second dose follows the first by 1 month and third dose follows the second dose by 5 months). No vaccines exist for other hepatitis viruses. 24. Serum alkaline phosphatase may be elevated in the diseases of which organ? A. Liver B. Salivary glands C. Spleen D. Heart E. Bladder The answer is: A Alkaline phosphatase originates from bone, liver, intestine, and placenta. Elevated levels of alkaline phosphatase occur in persons with parenchymal liver diseases (slight to moderate increases in many of these cases). Impaired biliary function also shows elevated levels of alkaline phosphatase in the absence of bone disease and pregnancy. Alkaline phosphatase is not increased in diseases of the salivary glands, spleen, heart, or bladder 25....
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This note was uploaded on 11/21/2009 for the course BIO 1B taught by Professor Carlson,mischel,power during the Summer '07 term at Berkeley.
- Summer '07