Hardy-Weingberg practice questions

# Hardy-Weingberg practice questions - = 0.2 a = q 2 + 1/2...

This preview shows pages 1–4. Sign up to view the full content.

Review: Population Genetics Problems Two types of questions: 1) Given H-W equilibrium and the frequency of various genotypes (e.g., AA, Aa or aa), what % of the population will have the allele A (or a)? 2) Given H-W equilibrium and the frequency of an allele (eg. A or a) , what % of the population will have genotypes AA, Aa or aa?

This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document
1) Given H-W equilibrium and the frequency of genotypes , what is the frequency of each allele ? For example, let's say we have the following genotype frequencies: AA =0.04 Aa = 0.32 aa = 0.64 A = p 2 + 1/2 (2pq) What is the frequency of the A allele ? p 2 q 2 2pq Under H-W, the frequency of these genotypes is given by: The general formula for determining the frequency of A is: So in this case, A = 0.04 + 1/2 (0.32)

This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: = 0.2 a = q 2 + 1/2 (2pq) We could also do this by calculating a first: a = 1-A = 1-0.2 = 0.8 Since the freq of A and a must add up to 1, we can calculate a by subtraction: So in this case, a = 0.64 + 1/2 (0.32) = 0.8 2) Given H-W equilibrium and the frequency of an allele , what % of the population will have various genotypes ? Genotypes are given by p 2 + 2pq+ q 2 , so: From #1: A = 0.2 a = 0.8 i) What is the frequency of homozygous AA individuals? AA => p 2 = 0.2*0.2 = 0.04 ii) What is the frequency of homozygous aa individuals? aa => q 2 = 0.8*0.8 = 0.64 i) What is the frequency of heterozygous Aa individuals? Aa => 2pq = 2*0.8*0.2 = 0.32...
View Full Document

## This note was uploaded on 11/22/2009 for the course BIO SCI 150 taught by Professor Geraldbergstrom during the Fall '08 term at Wisconsin Milwaukee.

### Page1 / 4

Hardy-Weingberg practice questions - = 0.2 a = q 2 + 1/2...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document
Ask a homework question - tutors are online