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Lecture_10_30 - Multi-component I-E synapse B has low...

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A B B A voltage voltage time time Multi-component I-E synapse B has low spontaneous What Can cause multi-components? A B B A voltage voltage time time Let’s look at PSP B has no spontaneous activity To do this it will be easier if We weakly stimulate A We note an inhibitory hyperpolarization followed by a depolarization How could you get this Two different receptors, one different neurotransmitter. First receptor is activated which opens a channel the has inhibitory E R , then a slower to open or longer lasting opening of the 2dn receptor which has an excitatory E R Two different receptors, two different neurotransmitters Metabotropic receptor that effects two channels at different times Note: definitions of I and E relative to AP threshold still applies
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