Lecture_10_30

Lecture_10_30 - A B B A voltage voltage time time...

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Unformatted text preview: A B B A voltage voltage time time Multi-component I-E synapse B has low spontaneous What Can cause multi-components? A B B A voltage voltage time time Lets look at PSP B has no spontaneous activity To do this it will be easier if We weakly stimulate A We note an inhibitory hyperpolarization followed by a depolarization How could you get this Two different receptors, one different neurotransmitter. First receptor is activated which opens a channel the has inhibitory E R , then a slower to open or longer lasting opening of the 2dn receptor which has an excitatory E R Two different receptors, two different neurotransmitters Metabotropic receptor that effects two channels at different times Note: definitions of I and E relative to AP threshold still applies P E P E Each line on the plots represent an action potential Excitatory neuron and synapse Inhibitory neuron and synapse D= Driver , F = Flexor, E = Extensor, P = Pacemaker, I = interneuron Rhythm Generating Circuits Pacemaker cell has monosynaptic inhibition on extensor extensor has normally have high spontaneous (pacemaker goes to flexor) voltage voltage time time V.A.3.d. Presynaptic cell is pacemaker and postsynaptic cell has a high level of spontaneous activity F D E Assume F and E have strong post-inhibitory rebound 1/2 Center Oscillator Rhythm Generating Circuits D= Driver , F = Flexor, E = Extensor, P = Pacemaker, I = interneuron D E F voltage voltage voltage time time time V.A.5. Half center oscillators (mutual inhibitory circuits) V.A.5.a Oscillations due to post-inhibitory rebound vol tage D F E D D F E tage voltage vol 1/2 Center Oscillator Rhythm Generating Circuits D= Driver , F = Flexor, E = Extensor, P = Pacemaker, I = interneuron What happens when you put pacemakers into these circuits? time time time V.A.5.b. Oscillations due to habituation What you will learn in this module. 1. In this module, we will move beyond simple circuits and study motor systems controlling the behavior of invertebrates, and study the swimming behavior of the Tritonia sea slug and the escape response of a crayfish. 2. In Tritonia, we will introduce a rhythmically oscillating swimming circuit 3. In Tritonia, we will see it is possible for a circuit to rhythmically oscillate independent of sensory feedback. A circuit exhibiting this behavior is referred to as a central pattern generator (CPG). 4. In Tritonia, we will re-emphasize the importance of connectivity, synaptic properties, and intrinsic cellular properties in producing the coordinated swimming pattern. Altering any of these variables may lead to a novel swimming behavior potentially beneficial or disastrous to the coordinated swimming pattern....
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Lecture_10_30 - A B B A voltage voltage time time...

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