Lect8_Slides

Lect8_Slides - Viruses – Part 1 Outline 1.  Structure...

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Unformatted text preview: Viruses – Part 1 Outline 1.  Structure 2.  Viral Life Cycle (Lysis vs Lysogeny) 5.  Viral Classification 4. Genome Replication Overview of Virus Structure •  Functions: –  Protection of genome –  Interaction with host cell •  Few different structures described –  Isoahedral –  Filamentous –  Asymmetrical Icosahedral Viruses Filamentous Viruses Asymmetrical Viruses Viral Life Cycle •  1. Attachment to host cell •  2. Genome entry •  3. Gene expression and genome replication. •  4. Virion assembly •  5. Exit and transmission Lysis vs Lysogeny Viral Classification •  Nature of genome •  Mechanism of production of mRNA •  Mechanism of producing new copies of the genome Seven Classes of Viruses (+) ssRNA Poliovirus Replication Retroviral Genome Replication Retroviral Reverse Transcription A tRNA serves as a primer for DNA synthesis. The genome has terminal repeats. Ends of Linear DNA Molecules Lost During Replication Telomerase “Fills In” the Recessed 5’ End Using Protein Primer Rolling Circle Replication Join-and-Cut Method ...
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