This preview shows page 1. Sign up to view the full content.
Unformatted text preview: Viruses Part 2 – Gene
1. Why is gene expression controlled?
2. Challenges faced for controlling gene
expression by RNA viruses
- prokaryotic vs. eukaryotic viruses 3. Strategies used by RNA viruses
- Regulated translation
Transcription into monocistronic mRNAs Gene Expression
Different genes expressed at
different points in the infection
Some proteins are needed at
higher concentrations than others. Gene Expression
During Infection –
Latent versus Infectious
Early versus late proteins ssRNA(+) bacterial virus ssRNA(+) eukaryotic virus VPg = covalently attached viral protein Cleavage of a Polyprotein Segmented Genome ssRNA(-) eukaryotic virus Alternative Splicing ssRNA(+) virus
transcription into monocistronic mRNAs ...
View Full Document
This note was uploaded on 11/23/2009 for the course MIMG 101 taught by Professor Bradley during the Winter '08 term at UCLA.
- Winter '08