Lab+3+Bone+Cart+Histo+Arms_withHistoReview

Lab+3+Bone+Cart+Histo+Arms_withHistoReview - Histo Review...

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Histo Review
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Week 3: Cartilage, Bone, Joints, and the Upper Extremity • Part 1: Cartilage histology • Part 2: Bone histology • Part 3: Joints • Part 4: Arm MM and bones
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Properties of Cartilage • Dominated by extracellular matrix – Mostly ground substance (proteoglycans, H 2 O) – Collagen fibers, sometimes elastin fibers – Cells are called chondrocytes ; these sit in small spaces within the matrix called lacunae • Avascular (rare for CT) • Semi-rigid
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Types of Cartilage • Hyaline cartilage – has a moderate amount of collagen fibers – joint surfaces, involved in bone formation • Fibrocartilage – contains lots of collagen fibers – intervertebral discs, pubic symphysis • Elastic cartilage – collagen and elastin fibers – ear, larynx, Eustachian tubes, epiglottis
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Functions of Cartilage • Support of body (intervertebral discs) • Support/protection against collapse (trachea) • Increase joint mobility by reducing friction • Template for bones in embryonic/growing skeleton
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Hyaline Cartilage lacuna chondrocyte
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Fibrocartilage
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Elastic Cartilage
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Development of Cartilage Appositional Interstitial MMW 6.11 Cell division at the perichondrium ECM hypertrophy creates more space (perichondrium and mitosis) (cell and ECM hypertrophy)
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This note was uploaded on 12/02/2009 for the course IB 131L taught by Professor Lewis during the Spring '09 term at Berkeley.

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Lab+3+Bone+Cart+Histo+Arms_withHistoReview - Histo Review...

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