MT1 histo review - Midterm 1 HistoReview Properties of...

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Unformatted text preview: Midterm 1 HistoReview Properties of epithelia Rests on basement membrane (aka basal lamina) Polarized : Apical, lateral, and basal sides of cells and tissues Cellular: little/no extracellular matrix Avascular Epithelial tissue classification: The formula Level of complexity + cell shape + epithelium + any surface modifications So: Simple/stratified/pseudostratified + squamous/cuboidal/columnar + epithelium + with cilia/microvilli/goblet cells/keratinizationetc. Or: transitional epithelium Mesotheliumspread: simple squamousepithelium Note fried eggappearance of cells (can also look like fish scales see next slide). Basement membrane underneath. 2007 Sarah Werning Endothelium = simple squamous epithelium lining blood vessels. Nuclei are the most obvious features. Longitudinal cut of blood vessel (above) Cross section of blood vessel (right) CT CT A basement membrane separates the single layer of cells in the SSE from the CT basal to it. CT SSE Submandibular gland, 100x Simple cuboidal epithelium 2007 Sarah Werning Submandibular gland, 100x Simple columnar epithelium 2007 Sarah Werning The nuclei of simple columnar epithelium are all at the same level, near the basal surface. Can have surface modifications like goblet cells,stereocilia, or microvilli. Simple columnar epithelium with stereocilia Note the nuclei are all at the same level (can be more variable). Stereocilia very long, few per cell, and somewhat hard to see. Colon mucosa, 100x Simple columnar epithelium with goblet cells 2007 Sarah Werning Stratified squamous epithelium Cells progressively flatter towards surface Looks like simple squamous, but many layers. To tell the difference: look for a basement membrane and CT in cross-section. Near the basement membrane, nuclei look denser, closer together. Stratified squamous epithelium with keratin keratinized not keratinized 2007 Sarah Werning This is skin from the volar (palmar) surface of the hand MMFig. 4-3f Stratified cuboidal epithelium is usually two cell layers thick. Like simple cuboidal epithelium, it surrounds ducts (but larger ones). Submandibular gland, 100x, Stratified columnar epithelium Beautiful! 2007 Sarah Werning Stratified columnar epithelium is rare. Look for similar looking nuclei. Bottom layer looks cuboidal, apical layer looks columnar. There is one layer of cells in [simple] pseudostratified columnar epithelium , but the nuclei are at different levels so it looks like there are more layers. Pseudostratified columnar epithelium with cilia Basement membrane >1 level of nuclei Cilia! LUMEN Ureter Well learn this later Transitional epithelium Deeper cells more columnar have a radial orientation, not a flator left-right orientation to the layers of cells. Apical cells range anywhere from round to flatin shape. How do I distinguish Simple cuboidalepithelium Simple squamous epithelium Nucleus:cytoplasmratio; amount of contact between neighboring cells; thickness of each cell. How do I distinguish...
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This note was uploaded on 12/02/2009 for the course IB 131L taught by Professor Lewis during the Spring '09 term at University of California, Berkeley.

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MT1 histo review - Midterm 1 HistoReview Properties of...

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