Nchem%202007%20Chapter16

Nchem%202007%20Chapter16 - 16.1 Age of onset of major...

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16.1 Age of onset of major depression
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16.2 Concordance rate for mood disorders among identical and fraternal twins
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16.3 The HPA axis
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16.4 Abnormalities in glucocorticoids (Part 1)
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16.5 Altered sleep architecture in depression
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16.7 Acute and long-term effects of MAO-Is on synaptic function MAO normally keeps level of free monoamines in presynaptic terminal very low. Acutely, inhibitors of MAO allow monoamine accumulation and thus increased release. As a result, long-term Rx with MAOI down-regulates postsynaptic receptors.
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16.8 Tricyclic antidepressants
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16.9 Relative specificity of several antidepressant drugs that depend on reuptake blockade
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Cymbalta (duloxetine) – an SNRI For the treatment of depression, Cymbalta offers relief from many symptoms of depression that may include loss of interest, associated anxiety, aches and pains, and mood. While the mechanism of action for Cymbalta is not fully known, its effects on depression may be due to increasing the activity of two chemicals in the central
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Nchem%202007%20Chapter16 - 16.1 Age of onset of major...

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