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BIO365R Spring 2008 Exam 2+Key

BIO365R Spring 2008 Exam 2+Key - Print your first initial...

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Print your first initial and last name: ___________________________________ 1 Your UTEID: ___________Your signature: ___________________________________ Biology 365R Exam II October 20, 2008 Take the exam in INK. Print your name at the top of each page and enter your UEID and sign above. If you make a mistake on a question or need additional room you can use the back of the same page. Please use complete sentences wherever possible. Take a deep breath and Good luck! 1 . Write an equation for the current that will flow into a postsynaptic cell in response to any given transmitter. On separate lines, write an explanation of each of the term in this equation. 2 . For a neuron whose resting potential is -70 mV and whose threshold is -50 mV fill out the following table for a number of synapses on this cell: Synapse Reversal potential Direction of positive Is synapse excitatory current across membrane (write “E”) or inhibi- Write “in”, “neither”, or tory (write “I”), or “out” neither (write “N”) 1 -80 mV ____________ ___________ 2 -70 mV ____________ ___________ 3 -55 mV ____________ ___________ 4 -30 mV ____________ ___________
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Print your first initial and last name: ___________________________________ 2 3 . LTP is believed to be a mechanism for learning and memory in the hippocampus. Fill in the blanks below: LTP stands for _______________________________________. It can be demonstrated by recording from a pyramidal cell in the CA1 region of hippocampus while stimulating a set of axons from neurons in the CA3 region that innervate this pyramidal cell. The following is a typical experiment showing LTP. The investigator applies shocks to activate the presynaptic axons. Initially these shocks are “test” shocks to measure the size of the synaptic potential produced on the CA1 pyramidal cell and are repeated at some low frequency. Then the investigator shocks the axons with a __________________ stimulus. Afterwards, the test shocks produce responses that are ___________________________. The L in LTP means the response ______________________________________. The change in the synaptic response is believed to be due to the receptor known as the _______ receptor. This receptor normally binds and responds to the transmitter ______________. Its name is derived from a chemical that acts as an ____________ for this receptor. This receptor is unique among the receptors we have considered in class because it is both __________-gated and ___________-gated. It is also unique among the other receptor types that bind this particular transmitter because this receptor, when opened, conducts ________ ions (give me the distinctive ion).
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BIO365R Spring 2008 Exam 2+Key - Print your first initial...

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