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study_guide_1 - What have we seen cAMP or Ca or IP3 mediate...

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PSL 431 Exam 1 Study Guide On the differences and similarities between the book and the lectures: In the instructors view, the principle difference is that the lectures a) is more molecular, we covered many more protein molecules in more detail, and b) we covered different and more detailed physiological examples (diseases, bodily phenomena such as saliva secretion, learning, addiction, etc.), to illustrate basic cellular principles than the book provides. But the underlying similarity can be appreciated from the Review Questions in the textbook on pgs. 130-131, 150, 175, 191, 311, 320, which are good study aids. And you will find can generally be answered either from the book or from the lecture notes. A crucially important feature of your study should be to integrate and correlate the various molecules across the lectures What physiological responses given throughout the lectures depend on activating GPCRs? Which GPCRs are involved, adrenergic, muscarinic, olfactory? Which G-proteins mediate which of these responses through the lectures?
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Unformatted text preview: What have we seen cAMP, or Ca++, or IP3, mediate through the lectures? What have we seen cholinergic and adrenergic stimulation mediate through the lectures? There are quite a few examples of such phenomena, which are NOT mediated by one of these? Be able to predict the movement of water and ions in response to electrochemical gradients. We have also seen several different types of action potentials: neuronal/skeletal, ventricular/atrial pacemaker, smooth muscle types. What molecules and ions (moving in which direction) underlie the depolarization, repolarization, plateau phase (if any) of these? How do these action potentials differ, how are they similar? There are a similar set of questions (and answers) for the various graded potentials we’ve seen, EPSPs, IPSPs. How do the physiological examples fit into these molecular and cellular phenomena Cystic fibrosis, cholera, salivary secretion, 1/1...
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