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Review page for metabolic pathways(2)

Review page for metabolic pathways(2) - Fed...

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NUTR 300 For Exam 2 Review of Metabolic Pathways Carbohydrates Fats (lipids) Proteins Catabolic Pathways Glycogenolysis Lipolysis Proteolysis SUBSTRATE GLYCOGEN TRIGLYCERIDES PROTEINS FED OR FASTED? FASTED FASTED FASTED Glycolysis β -oxidation Deamination& transamination SUBSTRATE GLUCOSE FATTY ACIDS AMINO ACIDS FED OR FASTED? BOTH FED AND FASTED FASTED FASTED Anabolic (Synthetic) Pathways Glycogenesis Lipogenesis Protein Synthesis PRODUCT GLYCOGEN FATTY ACIDS PROTEINS FED OR FASTED? FED FED FED Gluconeogenesis PRODUCT GLUCOSE FED OR FASTED? FASTED I can see why the above classifications might present a bit of confusion; gluconeogenesis is a synthetic pathway, but is not occurring as a result of insulin’s influence. The table below presents a different way of thinking of fed versus fasted pathways:
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Unformatted text preview: Fed state -Insulin’s influence Fasted state -Glucagon’s influence (and epinephrine & cortisol in prolonged fast) Emphasis Storage of fuels Mobilization of fuels from stores Carbohydrate s Glycolysis* and Glycogenesis Glycogenolysis and glycolysis* Fats Lipogenesis and Triglyceride synthesis Lipolysis and β-oxidation Ketogenesis will be a featured pathway of prolonged fasting or low carbohydrate diets Protein Protein synthesis Proteolysis and deamination and transamination to generate carbon skeletons for gluconeogenesis *Note: Glycolysis is going to be ongoing during fed and initial fasted states. Even in prolonged fasting, glycolysis will continue to be used in cells to generate energy....
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