341lecture33dec2sakai

341lecture33dec2sakai - Cell Biology 341 Weds December 2...

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Cell Biology 341 Weds., December 2, 2009 Today: Begin chapter 16: three types of filaments in the cytoskeleton Exam 3 2008 and end-of- chapter problem answers are posted on Sakai Office hours this week are Thursday, Dec 3, from 1-3 pm Exam Friday, Dec 4, covers chapters 12, 13, 14 and 15 (starting with slide 7 on October 30) Bring #2 pencils Last lecture: finished chapter 15 Receptor tyrosine kinases have both receptor and protein kinase activity Signal receptor tyrosine kinase forms dimer each subunit phosphorylates the other on the cytoplasmic domain The phosphates are binding sites for other proteins, such as an adaptor that binds the GEF called Sos Ras is a monomeric GTPase that is activated by nucleotide exchange Ras-GTP Ras-GTP MAP kinase module of 3 protein kinases in sequence
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Chapter 16: The Cytoskeleton A supporting network of protein filaments that constantly changes form to allow the cell to move, change shape and transport organelles and structures within the cell
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The cytoskeleton contains 3 types of filaments: Panel 16-1 page 968 Intermediate filaments 10 nm diameter Microtubules 25 nm diameter Actin filaments (microfilaments) 7 nm diameter Keratins, lamins form ropelike fibers
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This note was uploaded on 12/05/2009 for the course BIO 341 taught by Professor Noris during the Fall '09 term at Rhode Island.

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341lecture33dec2sakai - Cell Biology 341 Weds December 2...

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