341lecture17oct19sakai

341lecture17oct19sakai - Cell Biology 341 Monday, October...

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Cell Biology 341 Monday, October 19, 2009 Today: More asymmetrical properties of the plasma membrane Membrane protein structures Next: Chapter 11 on transport across membranes See the lipid bilayer tutorial at MolviZ.Org Last lecture: began chapter 10 Biological membranes are composed of a lipid bilayer and associated proteins Phospholipids, glycolipids and cholesterol/sterols Hydrophobic forces cause amphipathic lipids to form a continuous lipid bilayer with fluid properties Unsaturated fatty acid residues, shorter chain fatty acid tails and increased temperature all increase fluidity of membranes Saturated fatty acid residues, long chain fatty acid tails, and lower temperature all decrease fluidity Asymmetrical properties of plasma membrane: lipid composition of the monolayers differs Outside (+) charged relative to cytosolic face Carbohydrate residues only on noncytosolic face
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of oligosaccharides attached to glycolipids and glycoproteins , and longer polysaccharide chains attached to proteoglycans This layer is also called the glycocalyx It occurs only on the noncytosolic side Protects and lubricates the cell (increases solubility)
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341lecture17oct19sakai - Cell Biology 341 Monday, October...

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