1Lecture 14: Feb. 6Complex Patterns of Inheritance I: Beyond Mendel• T.H. Morgan & Sex-Linked Traits- study system - experiments & conclusions- sex chromosomes & sex determination•Sex-linked human diseases & disorders - X-linked traits• Linked Genes, Genetic Recombination & Linkage MapsDiscussion Activity This WeekGenetics Problem Set(week 6 folder)Essay 1 topic due Feb. 8Complete essay due by Feb. 22Check Qwizdom Points on SAMS https://cats.lsa.umich.edu/Chapters 13:279-298mutations in genes controlling eye color were some of the earliest mutations foundearly 1900s1933 Nobel prizeFLY LABSWhy use fruit flies (Drosophila melanogaster) as a model system?- small size and easy to culture in the lab- short generation time- produces lots (100s) of offspring per matingTracing a gene to a chromosome & sex-linkedinheritance first discovered in flies…T.H. Morgan’s firstmutantred eyesdesignated as w + or +white eyes - mutantdesignated as win flies, genes named after mutants+ always refers to wild typeearly 1900s1933 Nobel prize
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