BIO172W08Lec22CT - Biology 172 Lecture 22: Eukaryotic Gene...

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Lecture 22: Eukaryotic Gene Regulation II March 7, 2008 Today’s Outline 1. Finish Pre-transcriptional regulation (Wed lecture) 2. Regulation of transcription 3. Post-transcriptional 4. Post-translational control Announcements Make-up Policy on Quizzes: 1) excused absence, 2) make up quiz within one week, 3) go to ANY GSI’s office hours Biology 172
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Overview of Eukaryotic Gene Expression 1. 1. Pre-transcription Pre-transcription >> >> chromatin structure chromatin structure 1. 1. Transcription Transcription >> >> transcription factors transcription factors 2. 2. Post-transcriptional Post-transcriptional >> >> alternative mRNA splicing alternative mRNA splicing and differential mRNA and differential mRNA degradation degradation 3. 3. Translation Translation >> free or >> free or membrane-bound membrane-bound ribosomes ribosomes 4. 4. Post-translational Post-translational >> >> folding, chemical folding, chemical modification, transport, modification, transport, activation, degradation activation, degradation
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Comparison of Transcriptional Initiation in Prokaryotes and Eukaryotes Sigma factors bind to promoters at key sequences:
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This note was uploaded on 12/06/2009 for the course BIO 172 taught by Professor Clark during the Winter '08 term at University of Michigan.

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BIO172W08Lec22CT - Biology 172 Lecture 22: Eukaryotic Gene...

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