BIO172W08Lec34CTpdf-1 - Biology 172 L e c t u r e 3 6 E le...

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1 Lecture 36 – Electrical Signals: Animals April 11, 2008 Today s Outline 1. Principles of neural signaling 2. Membrane potentials - Movement of ions - Equilibrium potential - Calculating membrane potentials 3. Action potentials - Ion currents - Voltage-gated channels - Sodium-potassium pump - Propagation Announcements Exam 4: Tuesday April 22 7-9 PM Lectures 28-37 plus Discussions from March 27-April 11 Biology 172 Electrical signals: simple events that mediate complex processes • Electrical signals are generated by movements of ions across plasma membranes of nerve cells (neurons) • Provide fast and precise flow of information • Conducted (propagated) by neurons and (usually) converted to chemical signals for transfer to next neuron at a synapse • Pathway of information flow for reflexes: sensory neurons to interneurons to motor neurons Nervous system integrates neural signals Anatomy of a typical neuron Nerves are a bundle of axons from individual neurons Flow of information in the nervous system Membrane Potentials (again) • Typical membrane potential in neurons is -70 to -80 mV • Flow of ions is electrical current • Ions move in response to electrochemical gradients • Intracellular negatively charged proteins are
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This note was uploaded on 12/06/2009 for the course BIO 172 taught by Professor Clark during the Winter '08 term at University of Michigan.

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BIO172W08Lec34CTpdf-1 - Biology 172 L e c t u r e 3 6 E le...

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