BIO172W08Lec36CT - Biology 172 Lecture 36 Electrical...

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Lecture 36 – Electrical Signals: Animals April 11, 2008 Today’s Outline 1. Principles of neural signaling 2. Membrane potentials - Movement of ions - Equilibrium potential - Calculating membrane potentials 3. Action potentials - Ion currents - Voltage-gated channels - Sodium-potassium pump - Propagation Announcements Exam 4: Tuesday April 22 7-9 PM Lectures 28-37 plus Discussions from March 27-April 11 Biology 172
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Electrical signals: simple events that mediate complex processes Electrical signals are generated by movements of ions across plasma membranes of nerve cells (neurons) Provide fast and precise flow of information Conducted (propagated) by neurons and (usually) converted to chemical signals for transfer to next neuron at a synapse Pathway of information flow for reflexes: sensory neurons to interneurons to motor neurons Nervous system integrates neural signals
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Anatomy of a typical neuron
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Nerves are a bundle of axons from individual neurons Flow of information in the nervous system
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Membrane Potentials (again) Typical membrane potential in neurons is -70 to -80 mV Flow of ions is electrical current Ions move in response to electrochemical gradients Intracellular negatively charged proteins are organic anions
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This note was uploaded on 12/06/2009 for the course BIO 172 taught by Professor Clark during the Spring '08 term at University of Michigan.

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BIO172W08Lec36CT - Biology 172 Lecture 36 Electrical...

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