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Unformatted text preview: region of the bilayer. (4pt) If they state that cholesterol has a smaller polar, uncharged hydrophilic end (compared to phospholipids) but then dont directly state that this will enable it to pass through the hydrophobic portion of the bilayer. Instead, they postulate other odd mechanisms, focused on the size or structure of the molecule. (2-3 pts) recognize that cholesterol is amphiphatic but do not relate the small size of the polar group with that of phospholipids (1pt) answer that doesnt focus on the polar portion of the molecule. No points deducted if they include information about cholesterol filling gaps in the membrane or decreasing the fluidity (permeability) of the plasma membrane. This is technically correct, though irrelevant to the question. The size of the hydrophobic region of cholesterol or phospholipids has nothing to do with the rate of flipping. So its not a factor in deciding the grade....
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- Spring '08