LEARNING - Learning and Memory Lectures Aplysia Gill...

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Learning and Memory Lectures
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Aplysia Gill Withdrawal Reflex Aplysia will withdraw its gill. in response to 1) 2) Habituation: After repeated touches, Aplysia “learns” to no longer withdraw gill. Cellular mechanism of habituation: After repeated firing of action potentials in sensory neuron, Ca++ channels in the terminal deactivate. What is the effect of this deactivation? Additionally, vesicles are depleted from the terminal. What is the effect of this depletion?
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Sensitization or dishabituation: A noxious stimulus to the head or tail will increase the strength of the gill withdrawal reflex. Cellular mechanisms of sensitization and dishabituation: 10 Steps (8) AP in sensory neuron terminal is positive longer. (1) Serotonin released by facil interneuron onto terminal of siphon sensory neuron (4) this increases cAMP (2) (3) (5) (6) (7) (9) (10) Associative learning: Aplysia can learn to associate a non-noxious stimulus (e.g. A very light touch to the siphon) with a noxious stimulus (e.g. A strong poke to the head). Before conditioning, the animal will not exhibit the gill withdrawal reflex in
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This note was uploaded on 12/06/2009 for the course NPB 100 taught by Professor Chapman during the Fall '08 term at UC Davis.

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LEARNING - Learning and Memory Lectures Aplysia Gill...

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