Lecture 6 - Control of Gene Expression and Protein Function...

Info iconThis preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Control of Gene Expression and Protein Function Understand the difference between constitutive and inducible genes. Understand how protein activity within the prokaryotic and eukaryotic cell can be controlled. Understand the functioning of the Lac operon. Understand how transcription is controlled in eukaryotic cells. Be aware of the various DNA binding motifs that are known to exist. Understand how translation of mRNA can be controlled. Understand how the activity of proteins that have been synthesized can be affected. Central Dogma Gene Expression DNA RNA Protein Control of Gene Expression Control of Gene Expression Constitutive expression Rate of transcription of a gene is the same under all conditions Inducible Expression Vs. Repression Transcriptional Control of Gene Expression Induction Gene not normally expressed Gene expressed only when enzyme is needed and substrate for the enzyme is present Control of Gene Expression Transcriptional Activators Proteins that bind to specific DNA sequences upstream of a gene and increase transcription Transcriptional Control of Gene Expression Repression DNA binding protein blocks RNA Polymerase from transcribing the gene Control of Gene Expression Bacteria Transcriptional Control of Gene Expression Attenuation Stop transcription before it is completed Protein-dependent Rho factor Transcriptional Control of Gene Expression Attenuation Stop transcription before it is completed Protein-independent (stem-loop in mRNA) Attenuation Control of Gene Expression...
View Full Document

Page1 / 48

Lecture 6 - Control of Gene Expression and Protein Function...

This preview shows document pages 1 - 13. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online