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Molecular Biology BIMM100 Sample final 2009 Fall

Molecular Biology BIMM100 Sample final 2009 Fall - 1...

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1 Molecular Biology BIMM100 F INAL EXAM QUESTIONS FROM YEARS GONE BY 1) Describe the modifications that are found at the 5' end and the 3' end of most mRNAs in eukaryotic cells. 2) E. coli cells lysogenic for phage lambda are immune to infection by phage lambda. Explain the molecular basis for this immunity. 3) Consider two genes, A and B, that encode transcriptional regulators. The product of gene A represses transcription of gene B while the product of gene B activates transcription of gene A. Consider a cell that has considerable amounts of the product of gene B but very little of the product of gene A. How will transcription of genes A and B change over several generations of cell growth? 4) Please give 5 steps necessary for the elongation of a protein by one amino acid. 5) Describe the steps in a signal transduction pathway by which an extracellular signal can affect transcription of specific genes in the nucleus of a eukaryotic cell.
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